A Phase I human safety trial primarily to test the safety of the GeoVax DNA vaccine was approved by the Food and Drug Administration (FDA). This trial was initiated in early 2003 and satisfactorily concluded in mid-late 2004.
The GeoVax AIDS vaccine Phase I human trial was conducted at three [3] sites in the USA by the HVTN [HIV Trials Network - Division of the USA-National Institutes of Health.]
The GeoVax vaccine trial was successful and the GeoVax AIDS vaccine found to be safe.
Human trials started in the USA in April 2006 with trial participants receiving 1/10th does of GeoVax DNA [2 doses] and MVA [2 doses] AIDS vaccines. A second trial began in September 2006 with 30 participants. In this trial, participants received two [2] full doses of both the GeoVax DNA and MVA AIDS vaccines
Two human clinical trials are planned for 2007, one of which is a large scale Phase II Trial.